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The half-life is markedly longer in the elderly compared to younger subjects. Atenolol, in addition to its effects on survival, kupic ziolowe tenormin has shown other clinical benefits including reduced frequency of ventricular premature beats, reduced chest pain, and reduced enzyme elevation. Unlike propranolol or metoprolol, but like nadolol, TENORMIN undergoes little or no metabolism by the liver, and the absorbed portion is eliminated primarily by renal excretion. The following maximum oral dosages are recommended for elderly, renally-impaired patients and for patients with renal impairment due to other causes: Creatinine Clearance mL min. Following intravenous administration, peak plasma levels are reached within minutes. Some serious side effects that you should report to your healthcare provider immediately include sudden weight gain, chest pain, or irregular heartbeat.

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